Second place is up for grabs in Pool Five of the Heineken Cup when Biarritz and Ospreys lock horns on the French West coast.
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Biarritz are third on the ladder with 13 points after two wins from their five matches, while Ospreys have the same number of points after winning two and drawing one.
The home side have made a number of changes to their team with France international Imanol Harinordoquy starting at number eight, while veteran prop Sylvain Marconnet moves up from the bench.
In the backs, Julien Peyrelongue replaces Marcelo Bosch at fly-half with Benoît Baby making an appearance on the wing.
The Ospreys have made three changes with Shane Williams, Joe Bearman and Richard Hibbard all dropping down to the bench.
The home side are the favourites at 4/11 with
Bet365 to win the match with Ospreys on offer at 11/5. The draw can be backed at 22/1.
The Welsh side have been handed a six point start on the handicap betting market and you can back that outcome at 10/11.