Ulster will qualify for the Heineken Cup quarter-finals if they beat Clermont in their final Pool Four clash at the Stade Marcel Michelin.
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Ulster are top of Pool Four with 19 points thanks to four wins, while Clermont are in second spot on the ladder with 16 points.
Ulster boss Brian McLaughlin has been forced into one change with Darren Cave ruled out through injury with his place going to Ian Whitten.
Ulster have never won in France in 14 matches and they will be up against it when they face a Clermont side who have not lost at home in 38 matches.
Clermont have made a number of changes with Julien Bardy, Lee Byrne, Sitiveni Sivivatu, Julien Malzieu and Morgan Parra the only players to retain their places from their win over Aironi last weekend.
Clermont are seen as the 1/8 favourites with
Bet365, while Ulster are 5/1 to win their first ever match in France. The draw can be backed at 33/1.
The Irish side have been handed a 12 point start on the handicap market with odds of 10/11, while Clermont -12 are on offer at the same price.
